Jeff, a down on his luck office worker finds out he is the last living relative of horror novelist H.P. Lovecraft. What he doesn't know is that Lovecraft's monsters are real and will soon threaten the very existence of mankind. Jeff and his best friend Charlie are forced to embark on a perilous adventure and they enlist the help of high school acquaintance, Paul, a self proclaimed Lovecraft specialist. Together the three unlikely heroes must protect an alien relic and prevent the release of an acient evil, known as Cthulhu.
Based on the book of the same name by Matt Ruff, the anthology horror series follows 25-year-old Atticus Black, who joins up with his friend Letitia and his Uncle George to embark on a road trip across 1950s Jim Crow America to find his missing father. They must survive and overcome both the racist terrors of white America and the malevolent spirits that could be ripped from a Lovecraft paperback.